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Excess Mcm2–7 license dormant origins of replication that can be used under conditions of replicative stress
In late mitosis and early G1, replication origins are licensed for subsequent use by loading complexes of the minichromosome maintenance proteins 2–7 (Mcm2–7). The number of Mcm2–7 complexes loaded onto DNA greatly exceeds the number of replication origins used during S phase, but the function of th...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063885/ https://ncbi.nlm.nih.gov/pubmed/16754955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602108 |
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