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Characterisation of a novel ATR-dependent, Chk1-independent, intra-S phase checkpoint that suppresses initiation of replication in Xenopus
In most eukaryotes, replication origins fire asynchronously throughout S-phase according to a precise timing programme. When replication fork progression is inhibited, an intra-S phase checkpoint is activated which blocks further origin firing and stabilises existing replication forks to prevent the...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2004
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2701543/ https://ncbi.nlm.nih.gov/pubmed/15536124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.01400 |
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