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Centromeric DNA replication reconstitution reveals DNA loops and ATR checkpoint suppression
Half of human genome is made of repetitive DNA. However, mechanisms underlying replication of chromosome regions containing repetitive DNA are poorly understood. We reconstituted replication of defined human chromosome segments using Bacterial Artificial Chromosomes (BACs) in Xenopus laevis egg extr...
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| Publicado en: | Nat Cell Biol |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4939857/ https://ncbi.nlm.nih.gov/pubmed/27111843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3344 |
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