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How dormant origins promote complete genome replication
Many replication origins that are licensed by loading MCM2-7 complexes in G1 are not normally used. Activation of these dormant origins during S phase provides a first line of defence for the genome if replication is inhibited. When replication forks fail, dormant origins are activated within region...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329722/ https://ncbi.nlm.nih.gov/pubmed/21641805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2011.05.002 |
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