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Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

Only ∼10% of replication origins that are licensed by loading minichromosome maintenance 2-7 (MCM2-7) complexes are normally used, with the majority remaining dormant. If replication fork progression is inhibited, nearby dormant origins initiate to ensure that all of the chromosomal DNA is replicate...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: McIntosh, Debbie, Blow, J. Julian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475168/
https://ncbi.nlm.nih.gov/pubmed/22904560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012955
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