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Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses
Only ∼10% of replication origins that are licensed by loading minichromosome maintenance 2-7 (MCM2-7) complexes are normally used, with the majority remaining dormant. If replication fork progression is inhibited, nearby dormant origins initiate to ensure that all of the chromosomal DNA is replicate...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3475168/ https://ncbi.nlm.nih.gov/pubmed/22904560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012955 |
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