A carregar...
Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation
To prevent re-replication of DNA in a single cell cycle, the licensing of replication origins by Mcm2-7 is prevented during S and G2 phases. Animal cells achieve this by cell cycle regulated proteolysis of the essential licensing factor Cdt1 and inhibition of Cdt1 by geminin. Here we investigate the...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3481538/ https://ncbi.nlm.nih.gov/pubmed/22366459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.100883 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|