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Preferential Re-Replication of Drosophila Heterochromatin in the Absence of Geminin
To ensure genomic integrity, the genome must be duplicated exactly once per cell cycle. Disruption of replication licensing mechanisms may lead to re-replication and genomic instability. Cdt1, also known as Double-parked (Dup) in Drosophila, is a key regulator of the assembly of the pre-replicative...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2936543/ https://ncbi.nlm.nih.gov/pubmed/20838463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001112 |
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