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Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication
The six main minichromosome maintenance proteins (Mcm2–7), which presumably constitute the core of the replicative DNA helicase, are present in chromatin in large excess relative to the number of active replication forks. To evaluate the relevance of this apparent surplus of Mcm2–7 complexes in huma...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2008
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2449346/ https://ncbi.nlm.nih.gov/pubmed/18579778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803978105 |
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