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Origin Licensing Requires ATP Binding and Hydrolysis by the MCM Replicative Helicase
Loading of the six related Minichromosome Maintenance (MCM) proteins as head-to-head double hexamers during DNA replication origin licensing is crucial for ensuring once-per-cell-cycle DNA replication in eukaryotic cells. Assembly of these prereplicative complexes (pre-RCs) requires the Origin Recog...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4157578/ https://ncbi.nlm.nih.gov/pubmed/25087873 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.06.034 |
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