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Bidirectional eukaryotic DNA replication is established by quasi-symmetrical helicase loading
Bidirectional replication from eukaryotic DNA replication origins requires the loading of two ring-shaped Minichromosome Maintenance (MCM) helicases around DNA in opposite orientations. MCM loading is orchestrated by binding of the Origin Recognition Complex (ORC) to DNA, but how ORC coordinates sym...
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| Publicado no: | Science |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5608077/ https://ncbi.nlm.nih.gov/pubmed/28729513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan0063 |
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