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How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication
The eukaryotic replisome is a molecular machine that coordinates the Cdc45-MCM-GINS (CMG) replicative DNA helicase with DNA polymerases α, δ, and ε and other proteins to copy the leading- and lagging-strand templates at rates between 1 and 2 kb min(−1). We have now reconstituted this sophisticated m...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5222725/ https://ncbi.nlm.nih.gov/pubmed/27989442 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.017 |
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