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Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

The integrity of eukaryotic genomes requires rapid and regulated chromatin replication. How this is accomplished is still poorly understood. Using purified yeast replication proteins and fully chromatinized templates, we have reconstituted this process in vitro. We show that chromatin enforces DNA r...

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Bibliografski detalji
Izdano u:Mol Cell
Glavni autori: Kurat, Christoph F., Yeeles, Joseph T.P., Patel, Harshil, Early, Anne, Diffley, John F.X.
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2017
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222724/
https://ncbi.nlm.nih.gov/pubmed/27989438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.016
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