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Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks

The DNA damage checkpoint plays a crucial role in maintaining functional DNA replication forks when cells are exposed to genotoxic agents. In budding yeast, the protein kinases Mec1 (ATR) and Rad53 (Chk2) are especially important in this process. How these kinases act to stabilize DNA replication fo...

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Hlavní autoři: Segurado, Monica, Diffley, John F.X.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492668/
https://ncbi.nlm.nih.gov/pubmed/18593882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.477208
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