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Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks

The DNA damage checkpoint plays a crucial role in maintaining functional DNA replication forks when cells are exposed to genotoxic agents. In budding yeast, the protein kinases Mec1 (ATR) and Rad53 (Chk2) are especially important in this process. How these kinases act to stabilize DNA replication fo...

詳細記述

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書誌詳細
主要な著者: Segurado, Monica, Diffley, John F.X.
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492668/
https://ncbi.nlm.nih.gov/pubmed/18593882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.477208
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