लोड हो रहा है...
Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA
In response to DNA damage during S phase, cells slow DNA replication. This slowing is orchestrated by the intra-S checkpoint and involves inhibition of origin firing and reduction of replication fork speed. Slowing of replication allows for tolerance of DNA damage and suppresses genomic instability....
में बचाया:
| में प्रकाशित: | PLoS Genet |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2017
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5570505/ https://ncbi.nlm.nih.gov/pubmed/28806726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006958 |
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