Lataa...

Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA

In response to DNA damage during S phase, cells slow DNA replication. This slowing is orchestrated by the intra-S checkpoint and involves inhibition of origin firing and reduction of replication fork speed. Slowing of replication allows for tolerance of DNA damage and suppresses genomic instability....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS Genet
Päätekijät: Iyer, Divya Ramalingam, Rhind, Nicholas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570505/
https://ncbi.nlm.nih.gov/pubmed/28806726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006958
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!