Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates

The integrity of eukaryotic genomes requires rapid and regulated chromatin replication. How this is accomplished is still poorly understood. Using purified yeast replication proteins and fully chromatinized templates, we have reconstituted this process in vitro. We show that chromatin enforces DNA r...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Kurat, Christoph F., Yeeles, Joseph T.P., Patel, Harshil, Early, Anne, Diffley, John F.X.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cell Press 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222724/
https://ncbi.nlm.nih.gov/pubmed/27989438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.11.016
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