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Iron Accumulates in Huntington’s Disease Neurons: Protection by Deferoxamine
Huntington’s disease (HD) is a progressive neurodegenerative disorder caused by a polyglutamine-encoding CAG expansion in the huntingtin gene. Iron accumulates in the brains of HD patients and mouse disease models. However, the cellular and subcellular sites of iron accumulation, as well as signific...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3795666/ https://ncbi.nlm.nih.gov/pubmed/24146952 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077023 |
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