Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region

The inhibition properties and target sites of monoclonal antibodies (mAbs) Elec403, Elec408 and Elec410, generated against Electrophorus electricus acetylcholinesterase (AChE), have been defined previously using biochemical and mutagenesis approaches. Elec403 and Elec410, which bind competitively wi...

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Detaylı Bibliyografya
Asıl Yazarlar: Bourne, Yves, Renault, Ludovic, Essono, Sosthène, Mondielli, Grégoire, Lamourette, Patricia, Boquet, Didier, Grassi, Jacques, Marchot, Pascale
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795623/
https://ncbi.nlm.nih.gov/pubmed/24146971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077226
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