Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region

The inhibition properties and target sites of monoclonal antibodies (mAbs) Elec403, Elec408 and Elec410, generated against Electrophorus electricus acetylcholinesterase (AChE), have been defined previously using biochemical and mutagenesis approaches. Elec403 and Elec410, which bind competitively wi...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Bourne, Yves, Renault, Ludovic, Essono, Sosthène, Mondielli, Grégoire, Lamourette, Patricia, Boquet, Didier, Grassi, Jacques, Marchot, Pascale
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795623/
https://ncbi.nlm.nih.gov/pubmed/24146971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077226
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