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Structural Insights into Antibody Sequestering and Neutralizing of Na(+) Channel α-Type Modulator from Old World Scorpion Venom
The Old World scorpion Androctonus australis hector (Aah) produces one of the most lethal venoms for humans. Peptidic α-toxins AahI to AahIV are responsible for its potency, with AahII accounting for half of it. All four toxins are high affinity blockers of the fast inactivation phase of mammalian v...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3340158/ https://ncbi.nlm.nih.gov/pubmed/22371498 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315382 |
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