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Microfluidic Assembly of Lipid-based Oligonucleotide Nanoparticles

BACKGROUND: Oligonucleotides (ONs) have shown great promise as therapeutic agents for various diseases. It is necessary to provide a protocol for preparation of ON-loaded lipid nanoparticles (LNPs) in a reproducible manner on a laboratory scale. MATERIALS AND METHODS: A 3-inlet microfluidic (MF) chi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yu, Bo, Zhu, Jing, Xue, Weiming, Wu, Yun, Huang, Xiaomeng, Lee, L. James, Lee, Robert J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791325/
https://ncbi.nlm.nih.gov/pubmed/21498694
Tagiau: Ychwanegu Tag
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