Delivery of antisense oligodeoxyribonucleotide lipopolyplex nanoparticles assembled by microfluidic hydrodynamic focusing

A multi-inlet microfluidic hydrodynamic focusing (MF) system to prepare lipopolyplex (LP) containing Bcl-2 antisense deoxyoligonucleotide (ODN) was developed and evaluated. The lipopolyplex nanoparticles consist of ODN:protamine:lipids (1:0.3:12.5 wt/wt ratio) and the lipids included DC-Chol:egg PC:...

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Bibliografske podrobnosti
izdano v:J Control Release
Main Authors: Koh, Chee Guan, Zhang, Xulang, Liu, Shujun, Golan, Sharon, Yu, Bo, Yang, Xiaojuan, Guan, Jingjiao, Jin, Yan, Talmon, Yeshayahu, Muthusamy, Natarajan, Chan, Kenneth K, Byrd, John C., Lee, Robert J., Marcucci, Guido, Lee, L. James
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289903/
https://ncbi.nlm.nih.gov/pubmed/19716852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.08.019
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