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Microfluidic Assembly of Lipid-based Oligonucleotide Nanoparticles
BACKGROUND: Oligonucleotides (ONs) have shown great promise as therapeutic agents for various diseases. It is necessary to provide a protocol for preparation of ON-loaded lipid nanoparticles (LNPs) in a reproducible manner on a laboratory scale. MATERIALS AND METHODS: A 3-inlet microfluidic (MF) chi...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3791325/ https://ncbi.nlm.nih.gov/pubmed/21498694 |
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