Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes

Background. Based on a hollow-fiber system model of tuberculosis, we hypothesize that microbiologic failure and acquired drug resistance are primarily driven by low drug concentrations that result from pharmacokinetic variability. Methods. Clinical and pharmacokinetic data were prospectively collect...

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Bibliografiska uppgifter
Huvudupphovsmän: Pasipanodya, Jotam G., McIlleron, Helen, Burger, André, Wash, Peter A., Smith, Peter, Gumbo, Tawanda
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2013
Ämnen:
Major Articles and Brief Reports
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789573/
https://ncbi.nlm.nih.gov/pubmed/23901086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit352
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