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Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes
Background. Based on a hollow-fiber system model of tuberculosis, we hypothesize that microbiologic failure and acquired drug resistance are primarily driven by low drug concentrations that result from pharmacokinetic variability. Methods. Clinical and pharmacokinetic data were prospectively collect...
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| Glavni autori: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789573/ https://ncbi.nlm.nih.gov/pubmed/23901086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit352 |
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