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Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes
Background. Based on a hollow-fiber system model of tuberculosis, we hypothesize that microbiologic failure and acquired drug resistance are primarily driven by low drug concentrations that result from pharmacokinetic variability. Methods. Clinical and pharmacokinetic data were prospectively collect...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3789573/ https://ncbi.nlm.nih.gov/pubmed/23901086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit352 |
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