Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes

Background. Based on a hollow-fiber system model of tuberculosis, we hypothesize that microbiologic failure and acquired drug resistance are primarily driven by low drug concentrations that result from pharmacokinetic variability. Methods. Clinical and pharmacokinetic data were prospectively collect...

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Hlavní autoři: Pasipanodya, Jotam G., McIlleron, Helen, Burger, André, Wash, Peter A., Smith, Peter, Gumbo, Tawanda
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Major Articles and Brief Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789573/
https://ncbi.nlm.nih.gov/pubmed/23901086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit352
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