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Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes

Background. Based on a hollow-fiber system model of tuberculosis, we hypothesize that microbiologic failure and acquired drug resistance are primarily driven by low drug concentrations that result from pharmacokinetic variability. Methods. Clinical and pharmacokinetic data were prospectively collect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pasipanodya, Jotam G., McIlleron, Helen, Burger, André, Wash, Peter A., Smith, Peter, Gumbo, Tawanda
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789573/
https://ncbi.nlm.nih.gov/pubmed/23901086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit352
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