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A new evolutionary and pharmacokinetic-pharmacodynamic scenario for rapid emergence of resistance to single and multiple anti-tuberculosis drugs

The current understanding of the mechanism of anti-tuberculosis drug resistance has been shaped by the history of development of anti-tuberculosis drugs in the past 60 years and was arrived at as part of inductive generalization. Recently, these standard beliefs have been tested in controlled hollow...

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Autori principali: Pasipanodya, Jotam G., Gumbo, Tawanda
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183135/
https://ncbi.nlm.nih.gov/pubmed/21807559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2011.07.001
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