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A Meta-Analysis of Self-Administered vs Directly Observed Therapy Effect on Microbiologic Failure, Relapse, and Acquired Drug Resistance in Tuberculosis Patients

Background Preclinical studies and Monte Carlo simulations have suggested that there is a relatively limited role of adherence in acquired drug resistance (ADR) and that very high levels of nonadherence are needed for therapy failure. We evaluated the superiority of directly observed therapy (DOT) f...

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Main Authors: Pasipanodya, Jotam G., Gumbo, Tawanda
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669525/
https://ncbi.nlm.nih.gov/pubmed/23487389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/cit167
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