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Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN
We examined the ability of HIV-1 subtype C to develop resistance to the inhibitory lectins, griffithsin (GRFT), cyanovirin-N (CV-N) and scytovirin (SVN), which bind multiple mannose-rich glycans on gp120. Four primary HIV-1 strains cultured under escalating concentrations of these lectins became inc...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787538/ https://ncbi.nlm.nih.gov/pubmed/24074568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.07.019 |
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