Mechanisms of HIV-1 subtype C resistance to GRFT, CV-N and SVN

We examined the ability of HIV-1 subtype C to develop resistance to the inhibitory lectins, griffithsin (GRFT), cyanovirin-N (CV-N) and scytovirin (SVN), which bind multiple mannose-rich glycans on gp120. Four primary HIV-1 strains cultured under escalating concentrations of these lectins became inc...

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Hlavní autoři: Alexandre, Kabamba B., Moore, Penny L., Nonyane, Molati, Gray, Elin S., Ranchobe, Nthabeleng, Chakauya, Ereck, McMahon, James B., O’Keefe, Barry R., Chikwamba, Rachel, Morris, Lynn
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787538/
https://ncbi.nlm.nih.gov/pubmed/24074568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.07.019
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