Expanding the Structural Diversity of Polyketides by Exploring the Cofactor Tolerance of an Inline Methyltransferase Domain

[Image: see text] A strategy for introducing structural diversity into polyketides by exploiting the promiscuity of an in-line methyltransferase domain in a multidomain polyketide synthase in reported. In vitro investigations using the highly-reducing fungal polyketide synthase CazF revealed that it...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Winter, Jaclyn M., Chiou, Grace, Bothwell, Ian R., Xu, Wei, Garg, Neil K., Luo, Minkui, Tang, Yi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779521/
https://ncbi.nlm.nih.gov/pubmed/23837609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401723h
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