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Expanding the Structural Diversity of Polyketides by Exploring the Cofactor Tolerance of an Inline Methyltransferase Domain

[Image: see text] A strategy for introducing structural diversity into polyketides by exploiting the promiscuity of an in-line methyltransferase domain in a multidomain polyketide synthase in reported. In vitro investigations using the highly-reducing fungal polyketide synthase CazF revealed that it...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Winter, Jaclyn M., Chiou, Grace, Bothwell, Ian R., Xu, Wei, Garg, Neil K., Luo, Minkui, Tang, Yi
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779521/
https://ncbi.nlm.nih.gov/pubmed/23837609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol401723h
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