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Determination of in vivo B(max) and K(d) for [(11)C]GR103545, an agonist PET tracer for kappa opioid receptors: A study in nonhuman primates

The kappa opioid receptors (KOR) are involved in mood disorders and addictive conditions. In vivo imaging studies of this receptor in humans have not been reported due to the lack of a selective ligand. We employed a recently developed selective KOR agonist tracer, [(11)C]GR103545, and performed a s...

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書誌詳細
主要な著者: Tomasi, Giampaolo, Nabulsi, Nabeel, Zheng, Ming-Qiang, Weinzimmer, David, Ropchan, Jim, Blumberg, Laura, Brown-Proctor, Clive, Ding, Yu-Shin., Carson, Richard E., Huang, Yiyun
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775350/
https://ncbi.nlm.nih.gov/pubmed/23424192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.112672
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