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Determination of in vivo B(max) and K(d) for [(11)C]GR103545, an agonist PET tracer for kappa opioid receptors: A study in nonhuman primates
The kappa opioid receptors (KOR) are involved in mood disorders and addictive conditions. In vivo imaging studies of this receptor in humans have not been reported due to the lack of a selective ligand. We employed a recently developed selective KOR agonist tracer, [(11)C]GR103545, and performed a s...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775350/ https://ncbi.nlm.nih.gov/pubmed/23424192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.112672 |
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