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Determination of in vivo B(max) and K(d) for [(11)C]GR103545, an agonist PET tracer for kappa opioid receptors: A study in nonhuman primates
The kappa opioid receptors (KOR) are involved in mood disorders and addictive conditions. In vivo imaging studies of this receptor in humans have not been reported due to the lack of a selective ligand. We employed a recently developed selective KOR agonist tracer, [(11)C]GR103545, and performed a s...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3775350/ https://ncbi.nlm.nih.gov/pubmed/23424192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.112672 |
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