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Determination of in vivo B(max) and K(d) for [(11)C]GR103545, an agonist PET tracer for kappa opioid receptors: A study in nonhuman primates

The kappa opioid receptors (KOR) are involved in mood disorders and addictive conditions. In vivo imaging studies of this receptor in humans have not been reported due to the lack of a selective ligand. We employed a recently developed selective KOR agonist tracer, [(11)C]GR103545, and performed a s...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Tomasi, Giampaolo, Nabulsi, Nabeel, Zheng, Ming-Qiang, Weinzimmer, David, Ropchan, Jim, Blumberg, Laura, Brown-Proctor, Clive, Ding, Yu-Shin., Carson, Richard E., Huang, Yiyun
פורמט: Artigo
שפה:Inglês
יצא לאור: 2013
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3775350/
https://ncbi.nlm.nih.gov/pubmed/23424192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.112.112672
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