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Insights into Okazaki Fragment Synthesis by the T4 Replisome: THE FATE OF LAGGING-STRAND HOLOENZYME COMPONENTS AND THEIR INFLUENCE ON OKAZAKI FRAGMENT SIZE
In this study, we employed a circular replication substrate with a low priming site frequency (1 site/1.1 kb) to quantitatively examine the size distribution and formation pattern of Okazaki fragments. Replication reactions by the T4 replisome on this substrate yielded a patterned series of Okazaki...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774352/ https://ncbi.nlm.nih.gov/pubmed/23729670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.485961 |
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