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The Human Lagging Strand DNA Polymerase δ Holoenzyme Is Distributive

Polymerase δ is widely accepted as the lagging strand replicative DNA polymerase in eukaryotic cells. It forms a replication complex in the presence of replication factor C and proliferating cell nuclear antigen to perform efficient DNA synthesis in vivo. In this study, the human lagging strand holo...

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Détails bibliographiques
Auteurs principaux: Hu, Zhenxin, Perumal, Senthil K., Yue, Hongjun, Benkovic, Stephen J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493889/
https://ncbi.nlm.nih.gov/pubmed/22942285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.404319
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