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Subtype-specific Residues Involved in Ligand Activation of the Endothelial Differentiation Gene Family Lysophosphatidic Acid Receptors
Lysophosphatidic acid (LPA) is a ligand for three endothelial differentiation gene family G protein-coupled receptors, LPA(1–3). We performed computational modeling-guided mutagenesis of conserved residues in transmembrane domains 3, 4, 5, and 7 of LPA(1–3) predicted to interact with the glycerophos...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2008
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774115/ https://ncbi.nlm.nih.gov/pubmed/18316373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708847200 |
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