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Identification of Non-Lipid LPA(3) Antagonists by Virtual Screening
In the present study, we utilized virtual screening to identify LPA(3) antagonists. We have developed a three point structure-based pharmacophore model based on known LPA(3) antagonists. This model was used to mine the NCI database. Docking, pharmacophore development, and database mining produced ne...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483252/ https://ncbi.nlm.nih.gov/pubmed/18467108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2008.04.035 |
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