The Role of RIP2 in p38 MAPK Activation in the Stressed Heart

The activation of p38 MAPK by dual phosphorylation aggravates myocardial ischemic injury and depresses cardiac contractile function. SB203580, an ATP-competitive inhibitor of p38 MAPK and other kinases, prevents this dual phosphorylation during ischemia. Studies in non-cardiac tissue have shown rece...

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Autori principali: Jacquet, Sebastien, Nishino, Yasuhiro, Kumphune, Sarawut, Sicard, Pierre, Clark, James E., Kobayashi, Koichi S., Flavell, Richard A., Eickhoff, Jan, Cotten, Matt, Marber, Michael S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774113/
https://ncbi.nlm.nih.gov/pubmed/18310079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707750200
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