The Role of RIP2 in p38 MAPK Activation in the Stressed Heart

The activation of p38 MAPK by dual phosphorylation aggravates myocardial ischemic injury and depresses cardiac contractile function. SB203580, an ATP-competitive inhibitor of p38 MAPK and other kinases, prevents this dual phosphorylation during ischemia. Studies in non-cardiac tissue have shown rece...

Full description

Saved in:
Bibliographic Details
Main Authors: Jacquet, Sebastien, Nishino, Yasuhiro, Kumphune, Sarawut, Sicard, Pierre, Clark, James E., Kobayashi, Koichi S., Flavell, Richard A., Eickhoff, Jan, Cotten, Matt, Marber, Michael S.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774113/
https://ncbi.nlm.nih.gov/pubmed/18310079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707750200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items