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The Role of RIP2 in p38 MAPK Activation in the Stressed Heart
The activation of p38 MAPK by dual phosphorylation aggravates myocardial ischemic injury and depresses cardiac contractile function. SB203580, an ATP-competitive inhibitor of p38 MAPK and other kinases, prevents this dual phosphorylation during ischemia. Studies in non-cardiac tissue have shown rece...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2008
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774113/ https://ncbi.nlm.nih.gov/pubmed/18310079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707750200 |
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