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Developing small molecules to inhibit kinases unkind to the heart: p38 MAPK as a case in point

Over the last 40 years targeting G protein-coupled receptors and their ligands has had a major impact on the treatment of cardiovascular disease. However, the last decade has seen little progress and focus has shifted, particularly in the field of cancer biology, to downstream kinases. This review f...

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Detalhes bibliográficos
Main Authors: Marber, Michael S, Molkentin, Jeffery D., Force, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3026592/
https://ncbi.nlm.nih.gov/pubmed/21278838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddmec.2010.07.006
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