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Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf

The Unfolded Protein Response (UPR) maintains homeostasis in the endoplasmic reticulum (ER) and defends against ER stress, an underlying factor in various human diseases. During the UPR, numerous genes are activated that sustain and protect the ER. These responses are known to involve the canonical...

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Autori principali: Glover-Cutter, Kira M., Lin, Stephanie, Blackwell, T. Keith
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772064/
https://ncbi.nlm.nih.gov/pubmed/24068940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003701
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