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Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf
The Unfolded Protein Response (UPR) maintains homeostasis in the endoplasmic reticulum (ER) and defends against ER stress, an underlying factor in various human diseases. During the UPR, numerous genes are activated that sustain and protect the ER. These responses are known to involve the canonical...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3772064/ https://ncbi.nlm.nih.gov/pubmed/24068940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003701 |
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