Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf

The Unfolded Protein Response (UPR) maintains homeostasis in the endoplasmic reticulum (ER) and defends against ER stress, an underlying factor in various human diseases. During the UPR, numerous genes are activated that sustain and protect the ER. These responses are known to involve the canonical...

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Bibliographic Details
Main Authors: Glover-Cutter, Kira M., Lin, Stephanie, Blackwell, T. Keith
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772064/
https://ncbi.nlm.nih.gov/pubmed/24068940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003701
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