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Integration of the Unfolded Protein and Oxidative Stress Responses through SKN-1/Nrf

The Unfolded Protein Response (UPR) maintains homeostasis in the endoplasmic reticulum (ER) and defends against ER stress, an underlying factor in various human diseases. During the UPR, numerous genes are activated that sustain and protect the ER. These responses are known to involve the canonical...

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Autors principals: Glover-Cutter, Kira M., Lin, Stephanie, Blackwell, T. Keith
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772064/
https://ncbi.nlm.nih.gov/pubmed/24068940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003701
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