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Specific SKN-1/Nrf Stress Responses to Perturbations in Translation Elongation and Proteasome Activity
SKN-1, the Caenorhabditis elegans Nrf1/2/3 ortholog, promotes both oxidative stress resistance and longevity. SKN-1 responds to oxidative stress by upregulating genes that detoxify and defend against free radicals and other reactive molecules, a SKN-1/Nrf function that is both well-known and conserv...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3111486/ https://ncbi.nlm.nih.gov/pubmed/21695230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002119 |
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