Mitochondrial SKN-1/Nrf Mediates a Conserved Starvation Response

SKN-1/Nrf plays multiple essential roles in development and cellular homeostasis. We demonstrate that SKN-1 executes a specific and appropriate transcriptional response to changes in available nutrients, leading to metabolic adaptation. We isolated gain-of-function (gf) alleles of skn-1, affecting a...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Paek, Jennifer, Lo, Jacqueline Y., Narasimhan, Sri Devi, Nguyen, Tammy N., Glover-Cutter, Kira, Robida-Stubbs, Stacey, Suzuki, Takafumi, Yamamoto, Masayuki, Blackwell, T. Keith, Curran, Sean P.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774140/
https://ncbi.nlm.nih.gov/pubmed/23040073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.09.007
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares